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XB-PHENO-25750

Xla wt + dnmbp CRSPR, DeLay BD et al. (2019)

Experiment + Assay: Xla wt + dnmbp CRSPR + NF40-41 (in situ hybridization)
Background: Xla.pigmentedNasco
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR dnmbp gRNA1 dnmbp.L
dnmbp.S
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 40 to NF stage 41  
Anatomical Phenotypes: abnormal pronephric tubule morphology
Expression Phenotypes (2):
decreased amount atp1a1.L expression in distal tubule
decreased amount atp1a1.L expression in proximal tubule
Source: Fig. 9
Article: XB-ART-55764, PubMed