Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-24252

Xla Wt + ptpn11D61G, Langdon Y et al. (2012)

Experiment + Assay: Xla Wt + ptpn11D61G + NF35/36 (immunohistochemistry)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
DNA injection Tg(ptpn11D61G) ptpn11 (Xla)
 NF stage 1 embryo
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 35 and 36 Myh6 Ab2
Anatomical Phenotypes: abnormal cardiac atrium, abnormal cardiac ventricle, abnormal heart looping, abnormal heart morphology
Human Disease Associations: Noonan syndrome
Source: Fig. S1 C
Article: XB-ART-44762, PubMed