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Summary Expression Expr. PhenotypesPheno. Gene Literature (19)Lit. (19) GO Terms (48)GO (48) Nucleotides (125)Nucl. (125) Proteins (65)Prot. (65) Interactants (204)Interact. (204) Wiki
XB-GENEPAGE-479045
???displayGene.symbol???:
 smurf1

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SMAD specific E3 ubiquitin protein ligase 1

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xSMURF1 ( Nomenclature history )

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ubiquitin protein ligase

AI Protein Function :
smurf1 encodes an E3 ubiquitin ligase that ubiquitinates SMAD1/5/8 and RhoA, thereby modulating BMP and TGF‑β signaling pathways; it functions as a negative regulator of BMP‑induced transcription in de...[+]


InterPro :
C2 dom, C2 domain sf, E3 ub ligase SMURF1, E3 ubiq-protein ligase, [+]

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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