Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (4)Lit. (4) GO Terms (23)GO (23) Nucleotides (149)Nucl. (149) Proteins (63)Prot. (63) Interactants (45)Interact. (45) Wiki
XB-GENEPAGE-961780
???displayGene.symbol???:
 egln2

???displayGene.name???: 
egl-9 family hypoxia-inducible factor 2

???displayGene.synonyms???
phd1 ( Nomenclature history )

???displayGene.geneFunction???
EGL-Nine (EGLN) protein

AI Protein Function :
egln2 is an oxygen‑dependent prolyl‑4‑hydroxylase that hydroxylates HIF‑α subunits, directing them to proteasomal degradation and thereby regulating hypoxia‑inducible factor stability; it functions in ...[+]


InterPro :
Pro 4 hyd alph, Oxoglu/Fe-dep dioxygenase, HIF prolyl hydroxylases, Pro 4 hyd alph FE2OG OXY

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info