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Summary Expression Expr. PhenotypesPheno. Gene Literature (21)Lit. (21) GO Terms (69)GO (69) Nucleotides (60)Nucl. (60) Proteins (39)Prot. (39) Interactants (365)Interact. (365) Wiki
XB-GENEPAGE-852782
???displayGene.symbol???:
 ndp

???displayGene.name???: 
norrin cystine knot growth factor NDP

???displayGene.synonyms???
evr2 , fevr , norrin , xnorrin ( Nomenclature history )

???displayGene.geneFunction???
coagulation factor; activates the Wnt/beta-catenin pathway

AI Protein Function :
ndp encodes a secreted signaling ligand that activates canonical Wnt/β‑catenin signaling through Frizzled‑4, localizes to the extracellular space and associates with the plasma membrane of target cells...[+]


InterPro :
Cys knot C, Norrie dis, Cystine-knot cytokine, DAN

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

MIM:
NORRIE DISEASE; ND [+]

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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