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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (14)GO (14) Nucleotides (106)Nucl. (106) Proteins (52)Prot. (52) Interactants (64)Interact. (64) Wiki
XB-GENEPAGE-1013087
???displayGene.symbol???:
 gan

???displayGene.name???: 
gigaxonin

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes

AI Protein Function :
gan encodes a BTB‑Kelch domain protein that functions as an adaptor for Cullin‑3 ubiquitin ligase complexes, regulating degradation of intermediate filament proteins; it is expressed in the developing ...[+]


InterPro :
BTB-kelch protein, BTB/POZ dom, Kelch 1, SKP1/BTB/POZ sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
giant axonal neuropathy 1

MIM:
GIANT AXONAL NEUROPATHY 1, AUTOSOMAL RECESSIVE; GAN1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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