Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (50)GO (50) Nucleotides (118)Nucl. (118) Proteins (58)Prot. (58) Interactants (53)Interact. (53) Wiki
XB-GENEPAGE-855618
???displayGene.symbol???:
 appl2

???displayGene.name???: 
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

???displayGene.synonyms???
dip13b ( Nomenclature history )

???displayGene.geneFunction???
signal transduction

AI Protein Function :
appl2 encodes a membrane‑associated signaling adaptor protein that binds phosphoinositides and interacts with early endosomal compartments to regulate Akt/PKB signaling, neuronal differentiation, and c...[+]


InterPro :
AH/BAR dom sf, PH domain, PH-like dom sf, PTB/PI dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info