Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (44)Lit. (44) GO Terms (27)GO (27) Nucleotides (68)Nucl. (68) Proteins (31)Prot. (31) Interactants (211)Interact. (211) Wiki
XB-GENEPAGE-1017476
???displayGene.symbol???:
 dio2

???displayGene.name???: 
deiodinase, iodothyronine, type 2

???displayGene.synonyms???
deiodinase II , DI-2 , type 2 deiodinase , type II iodothyronine deiodinase ( Nomenclature history )

???displayGene.geneFunction???
thyroxine 5'-deiodinase

AI Protein Function :
dio2 encodes a selenocysteine‑containing deiodinase enzyme that catalyzes outer‑ring deiodination of thyroxine (T4) to produce triiodothyronine (T3), thereby activating thyroid hormone signaling; the p...[+]


InterPro :
Iodothyronine deiodinase, Iodothyronine deiodinase AS, Thioredoxin-like sf, Thioredoxin domain

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info