Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (99)Lit. (99) GO Terms (25)GO (25) Nucleotides (93)Nucl. (93) Proteins (35)Prot. (35) Interactants (861)Interact. (861) Wiki
XB-GENEPAGE-6258962
???displayGene.symbol???:
 lefty1

???displayGene.name???: 
left-right determination factor 1

???displayGene.synonyms???
antivin , atv , leftb , lefty , lefty-1 , lefty-a [+] ( Nomenclature history )

AI Protein Function :
lefty1 is a secreted TGF‑beta family signaling molecule that antagonizes Nodal activity, thereby restricting mesoderm induction and shaping left‑right axis formation; it is expressed in the dorsal blas...[+]


InterPro :
TGF-beta-rel, Cystine-knot cytokine, TGFb CS, TGF-b propeptide, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? lefty-har183      


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info