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Summary Expression Expr. PhenotypesPheno. Gene Literature (7)Lit. (7) GO Terms (22)GO (22) Nucleotides (314)Nucl. (314) Proteins (56)Prot. (56) Interactants (152)Interact. (152) Wiki
XB-GENEPAGE-491635
???displayGene.symbol???:
 sesn1

???displayGene.name???: 
sestrin 1

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nuclear factor XPA26-T2 , PA26 , XPA26 ( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein

AI Protein Function :
sesn1 encodes a cytoplasmic stress‑response protein that acts as a negative regulator of mTORC1 signaling, promotes autophagy, and protects cells from oxidative damage; it is expressed in the brain, ey...[+]


InterPro :
Sestrin, AhpD-like

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info