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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (19)GO (19) Nucleotides (41)Nucl. (41) Proteins (28)Prot. (28) Interactants (117)Interact. (117) Wiki
XB-GENEPAGE-483035
???displayGene.symbol???:
 ctla4

???displayGene.name???: 
cytotoxic T-lymphocyte associated protein 4

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
immunoglobulin

AI Protein Function :
ctla4 is a membrane‑bound receptor that negatively regulates T‑cell activation by competing with CD28 for B7‑1 (CD80) and B7‑2 (CD86) ligands, resulting in decreased interleukin‑2 production and suppre...[+]


InterPro :
CTLA4, CTLA4/CD28, Ig-like dom sf, Ig-like fold, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
type 1 diabetes mellitus 12 [+]

MIM:
CELIAC DISEASE, SUSCEPTIBILITY TO, 3; CELIAC3 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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