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Summary Expression Expr. PhenotypesPheno. Gene Literature (100)Lit. (100) GO Terms (29)GO (29) Nucleotides (125)Nucl. (125) Proteins (64)Prot. (64) Interactants (472)Interact. (472) Wiki
XB-GENEPAGE-479924
???displayGene.symbol???:
 slc12a1

???displayGene.name???: 
solute carrier family 12 member 1

???displayGene.synonyms???
Na-K-2Cl cotransporter , NKCC-2 , NKCC2 , XNKCC2 ( Nomenclature history )

???displayGene.geneFunction???
transmembrane solute exchange

AI Protein Function :
slc12a1 is a membrane-bound Na⁺‑K⁺‑2Cl⁻ cotransporter of the solute carrier family 12 that mediates electroneutral uptake of sodium, potassium and chloride ions; it functions in ion reabsorption and os...[+]


InterPro :
AA-permease/SLC12A dom, AA permease N, SLC12 C, Slc12a1, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Bartter disease type 1

MIM:
BARTTER SYNDROME, TYPE 1, ANTENATAL; BARTS1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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