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Summary Expression Expr. PhenotypesPheno. Gene Literature (969)Lit. (969) GO Terms (82)GO (82) Nucleotides (271)Nucl. (271) Proteins (68)Prot. (68) Interactants (2525)Interact. (2525) Wiki
XB-GENEPAGE-478788
???displayGene.symbol???:
 tbxt

???displayGene.name???: 
T-box transcription factor T

???displayGene.synonyms???
bra , brachyury , ntl , t , t-a , t-b [+] ( Nomenclature history )

???displayGene.geneFunction???
T-box transcription factor,. Ortholog to the murine brachury or T gene, mutations in which cause defects in tail development. Immediate-early transcriptional response to mesoderm induction.

AI Protein Function :
tbxt is a T‑box transcription factor localized to the nucleus that regulates mesoderm formation and notochord development, controlling posterior axis elongation and gastrulation movements. It activates...[+]


InterPro :
T-box sf, p53-like TF DNA-bd, TF T-box CS, TF T-box, [+]

???displayGene.geneInteractants???
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Diseases: 


MIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]

External Links:
GEO Series :
GSE48663, GSE96655, GSE122551.
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tgas116l23      


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