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Summary Expression Expr. PhenotypesPheno. Gene Literature (40)Lit. (40) GO Terms (241)GO (241) Nucleotides (219)Nucl. (219) Proteins (53)Prot. (53) Interactants (815)Interact. (815) Wiki
XB-GENEPAGE-491432
???displayGene.symbol???:
 pten

???displayGene.name???: 
phosphatase and tensin homolog

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
protein tyrosine phosphatase

AI Protein Function :
pten encodes a phosphatidylinositol‑3,4,5‑trisphosphate 3‑phosphatase that dephosphorylates PIP3 to PIP2, thereby antagonizing PI3K/AKT signaling and limiting cell proliferation, survival and migration...[+]


InterPro :
Tyr Pase cat, Tensin phosphatase, Bifunc PIno P3 Pase/Pase PTEN, Tyr Pase AS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Cowden syndrome 1 [+]

MIM:
THYROID CANCER, NONMEDULLARY, 2; NMTC2 [+]

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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