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Summary Expression Expr. PhenotypesPheno. Gene Literature (24)Lit. (24) GO Terms (78)GO (78) Nucleotides (305)Nucl. (305) Proteins (57)Prot. (57) Interactants (549)Interact. (549) Wiki
XB-GENEPAGE-6258451
???displayGene.symbol???:
 cbl

???displayGene.name???: 
Cbl proto-oncogene, E3 ubiquitin protein ligase

???displayGene.synonyms???
c-cbl , rnf55 ( Nomenclature history )

AI Protein Function :
cbl encodes an E3 ubiquitin‑protein ligase that negatively regulates receptor tyrosine kinase signaling by promoting ubiquitination and degradation of target receptors; it modulates MAPK cascade activi...[+]


InterPro :
Znf RING, Adaptor Cbl SH2-like, SH2 dom sf, Znf RING CS, [+]

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Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia

MIM:
JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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