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Summary Expression Expr. PhenotypesPheno. Gene Literature (10)Lit. (10) GO Terms (59)GO (59) Nucleotides (94)Nucl. (94) Proteins (51)Prot. (51) Interactants (21)Interact. (21) Wiki
XB-GENEPAGE-6065246
???displayGene.symbol???:
 casr

???displayGene.name???: 
calcium-sensing receptor

???displayGene.synonyms???
gprc2a , v2rF-1 ( Nomenclature history )

???displayGene.geneFunction???
Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily

AI Protein Function :
casr is a plasma‑membrane G‑protein coupled receptor that senses extracellular calcium and activates phospholipase C signaling, causing intracellular calcium release; it modulates calcium homeostasis a...[+]


InterPro :
GPCR 3 Ca sens rcpt-rel, GPCR 3, GPCR 3 CS, ANF lig-bd rcpt, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial hypocalciuric hypercalcemia 1 [+]

MIM:
HYPOPARATHYROIDISM, FAMILIAL ISOLATED, 1; FIH1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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