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Summary Expression Expr. PhenotypesPheno. Gene Literature (13)Lit. (13) GO Terms (36)GO (36) Nucleotides (141)Nucl. (141) Proteins (47)Prot. (47) Interactants (381)Interact. (381) Wiki
XB-GENEPAGE-6033924
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 dot1l

???displayGene.name???: 
DOT1-like histone H3K79 methyltransferase

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( Nomenclature history )

???displayGene.geneFunction???
Putative protein methyltransferase involved in meiosis and transcriptional silencing (Dot1)

AI Protein Function :
dot1l encodes a nuclear histone methyltransferase that specifically methylates histone H3 lysine 79, thereby regulating transcriptional activation of target genes; it is involved in heart morphogenesis...[+]


InterPro :
SAM-dependent MTases, H3-K79 meTrfase, DOT1 dom

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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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