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Summary Expression Expr. PhenotypesPheno. Gene Literature (42)Lit. (42) GO Terms (108)GO (108) Nucleotides (89)Nucl. (89) Proteins (55)Prot. (55) Interactants (558)Interact. (558) Wiki
XB-GENEPAGE-485175
???displayGene.symbol???:
 ret

???displayGene.name???: 
ret proto-oncogene

???displayGene.synonyms???
c-ret , cret , X-ret , xret ( Nomenclature history )

???displayGene.geneFunction???
tyrosine kinase receptor for GDNF ligand

AI Protein Function :
ret encodes a membrane‑bound receptor tyrosine kinase that binds glial cell line‑derived neurotrophic factor (GDNF) family ligands and activates MAPK and PI3K signaling pathways; it is localized to the...[+]


InterPro :
Protein kinase ATP BS, Kinase-like dom sf, Prot kinase dom, Ser-Thr/Tyr kinase cat dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
multiple endocrine neoplasia type 2A [+]

MIM:
CENTRAL HYPOVENTILATION SYNDROME, CONGENITAL, 1; CCHS1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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