Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (74)GO (74) Nucleotides (123)Nucl. (123) Proteins (80)Prot. (80) Interactants (33)Interact. (33) Wiki
XB-GENEPAGE-1014027
???displayGene.symbol???:
 shank3

???displayGene.name???: 
SH3 and multiple ankyrin repeat domains 3

???displayGene.synonyms???
LOC108711262 , LOC108713014 , prosap2 , psap2 , spank-2 [-] ( Nomenclature history )

???displayGene.geneFunction???
Ankyrin repeat

AI Protein Function :
shank3 encodes a postsynaptic density scaffold protein that organizes glutamatergic synapses, mediates dendritic spine morphogenesis, and regulates synaptic signaling and excitatory synapse formation. ...[+]


InterPro :
SH3-like dom sf, PDZ 6, Ankyrin rpt, SAM, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
schizophrenia 15 [+]

MIM:
PHELAN-MCDERMID SYNDROME; PHMDS [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info