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Summary Expression Expr. PhenotypesPheno. Gene Literature (5)Lit. (5) GO Terms (24)GO (24) Nucleotides (117)Nucl. (117) Proteins (46)Prot. (46) Interactants (342)Interact. (342) Wiki
XB-GENEPAGE-964333
???displayGene.symbol???:
 egln3

???displayGene.name???: 
egl-9 family hypoxia-inducible factor 3

???displayGene.synonyms???
PHD28 , phd3 ( Nomenclature history )

???displayGene.geneFunction???
EGL-Nine (EGLN) protein

AI Protein Function :
egln3 encodes a prolyl 4‑hydroxylase that hydroxylates HIF1α, leading to proteasomal degradation under normoxia; it modulates hypoxia‑induced transcription, influences apoptosis, regulates angiogenic s...[+]


InterPro :
Pro 4 hyd alph, Oxoglu/Fe-dep dioxygenase, HIF prolyl hydroxylases, Pro 4 hyd alph FE2OG OXY

???displayGene.geneInteractants???
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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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