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Summary Expression Expr. PhenotypesPheno. Gene Literature (65)Lit. (65) GO Terms (82)GO (82) Nucleotides (163)Nucl. (163) Proteins (51)Prot. (51) Interactants (729)Interact. (729) Wiki
XB-GENEPAGE-487419
???displayGene.symbol???:
 smo

???displayGene.name???: 
smoothened, frizzled class receptor

???displayGene.synonyms???
smoothened , XSmo , X-smoothened ( Nomenclature history )

???displayGene.geneFunction???
hedgehog signal transduction

AI Protein Function :
smo encodes a seven‑transmembrane G‑protein‑coupled receptor that transduces Hedgehog signals. It functions as a membrane‑bound receptor localized to the plasma membrane and primary cilium, where it pr...[+]


InterPro :
Frizzled dom sf, Frizzled/Smoothened TM, Frizzled dom, Frizzled/SFRP, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
basal cell carcinoma

MIM:
BASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 1; BCC1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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