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Summary Expression Expr. PhenotypesPheno. Gene Literature (19)Lit. (19) GO Terms (163)GO (163) Nucleotides (81)Nucl. (81) Proteins (48)Prot. (48) Interactants (753)Interact. (753) Wiki
XB-GENEPAGE-5938587
???displayGene.symbol???:
 erbb2

???displayGene.name???: 
erb-b2 receptor tyrosine kinase 2

???displayGene.synonyms???
LOC108702492 , XerbB2 ( Nomenclature history )

???displayGene.geneFunction???
epidermal growth factor receptor

AI Protein Function :
erbb2 encodes a transmembrane receptor tyrosine kinase that localizes to the plasma membrane and endocytic vesicles and functions as a signaling molecule activating MAPK/ERK and PI3K/AKT pathways; it i...[+]


InterPro :
Egfr JX dom, Furin-like Cys-rich dom, Furin repeat, GF recep IV, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
stomach cancer [+]

MIM:
DIFFUSE GASTRIC AND LOBULAR BREAST CANCER SYNDROME; DGLBC [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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