Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (28)Lit. (28) GO Terms (63)GO (63) Nucleotides (268)Nucl. (268) Proteins (44)Prot. (44) Interactants (601)Interact. (601) Wiki
XB-GENEPAGE-5900654
???displayGene.symbol???:
 cdk4

???displayGene.name???: 
cyclin-dependent kinase 4

???displayGene.synonyms???
xcdk4 ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
cdk4 is a cyclin‑dependent serine/threonine kinase that drives G1‑phase progression by phosphorylating retinoblastoma protein, promoting cell cycle entry. It functions as part of cyclin D‑cdk4 complexe...[+]


InterPro :
Protein kinase ATP BS, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


MIM:
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3; CMM3

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info