Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (66)Lit. (66) GO Terms (60)GO (60) Nucleotides (60)Nucl. (60) Proteins (37)Prot. (37) Interactants (782)Interact. (782) Wiki
XB-GENEPAGE-950264
???displayGene.symbol???:
 hcn1

???displayGene.name???: 
hyperpolarization activated cyclic nucleotide gated potassium channel 1

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
K+-channel ERG and related proteins, contain PAS/PAC sensor domain

AI Protein Function :
hcn1 encodes a hyperpolarization‑activated cyclic nucleotide‑gated (HCN) channel that functions as a membrane‑bound ion channel mediating the pacemaker current (Ih) which regulates neuronal excitabilit...[+]


InterPro :
cNMP-bd-like, cNMP-bd dom, K chnl volt-dep EAG/ELK/ERG, cNMP-bd CS, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
generalized epilepsy with febrile seizures plus

MIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 24; DEE24

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info