Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (29)GO (29) Nucleotides (40)Nucl. (40) Proteins (22)Prot. (22) Interactants (96)Interact. (96) Wiki
XB-GENEPAGE-6461261
???displayGene.symbol???:
 aire

???displayGene.name???: 
autoimmune regulator

???displayGene.synonyms???
aire1 , apeced , aps1 , apsi , pga1 [-] ( Nomenclature history )

AI Protein Function :
aire encodes a nuclear transcription factor with SAND and PHD domains that functions in thymic epithelial cells to regulate expression of tissue‑restricted antigens, contributing to central immune tole...[+]


InterPro :
Znf PHD, Zinc finger PHD-type CS, Znf FYVE PHD, Znf PHD-finger, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
autoimmune polyendocrine syndrome type 1

MIM:
AUTOIMMUNE POLYENDOCRINE SYNDROME, TYPE I, WITH OR WITHOUT REVERSIBLE METAPHYSEA

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info