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Summary Expression Expr. PhenotypesPheno. Gene Literature (5)Lit. (5) GO Terms (41)GO (41) Nucleotides (147)Nucl. (147) Proteins (47)Prot. (47) Interactants (65)Interact. (65) Wiki
XB-GENEPAGE-1017115
???displayGene.symbol???:
 egln1

???displayGene.name???: 
egl-9 family hypoxia-inducible factor 1

???displayGene.synonyms???
phd2 , PHD45 ( Nomenclature history )

???displayGene.geneFunction???
EGL-Nine (EGLN) protein

AI Protein Function :
egln1 encodes an oxygen‑dependent prolyl hydroxylase that hydroxylates HIF‑1α, promoting its proteasomal degradation and thereby modulating hypoxia signaling; the protein functions as a key regulator o...[+]


InterPro :
Znf MYND, Pro 4 hyd alph, Oxoglu/Fe-dep dioxygenase, HIF prolyl hydroxylases, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial erythrocytosis 3

MIM:
ERYTHROCYTOSIS, FAMILIAL, 3; ECYT3 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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