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Summary Expression Expr. PhenotypesPheno. Gene Literature (11)Lit. (11) GO Terms (64)GO (64) Nucleotides (221)Nucl. (221) Proteins (60)Prot. (60) Interactants (157)Interact. (157) Wiki
XB-GENEPAGE-5909319
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 arhgef2

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Rho/Rac guanine nucleotide exchange factor 2

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XLfc ( Nomenclature history )

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guanine nucleotide exchange factor

AI Protein Function :
arhgef2 is a Rho guanine nucleotide exchange factor that activates RhoA signaling, regulates actin filament organization and cell migration. It functions in neuronal differentiation, axon guidance and ...[+]


InterPro :
PH 16, DH-domain, DBL dom sf, PH domain, [+]

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Diseases: 


Disease Ontology:
neurodevelopmental disorder with midbrain and hindbrain malformations

MIM:
NEURODEVELOPMENTAL DISORDER WITH MIDBRAIN AND HINDBRAIN MALFORMATIONS; NEDMHM

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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