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Summary Expression Expr. PhenotypesPheno. Gene Literature (15)Lit. (15) GO Terms (140)GO (140) Nucleotides (96)Nucl. (96) Proteins (44)Prot. (44) Interactants (476)Interact. (476) Wiki
XB-GENEPAGE-484031
???displayGene.symbol???:
 igf1r

???displayGene.name???: 
insulin like growth factor 1 receptor

???displayGene.synonyms???
igf-1r , xIGF-1R , xigf1r , xIGFR , XTK2 [-] ( Nomenclature history )

???displayGene.geneFunction???
growth factor receptor, contains protein kinase domain

AI Protein Function :
igf1r is a transmembrane receptor tyrosine kinase that binds IGF1 and IGF2, activating PI3K‑Akt and MAPK cascades to promote cell proliferation, survival and differentiation; expression is reported in ...[+]


InterPro :
Furin repeat, Rcpt L-dom sf, Kinase-like dom sf, Tyr kinase rcpt 2 CS, [+]

???displayGene.geneInteractants???
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Diseases: 


MIM:
INSULIN-LIKE GROWTH FACTOR I, RESISTANCE TO; IGF1RES

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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