Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (38)Lit. (38) GO Terms (77)GO (77) Nucleotides (32)Nucl. (32) Proteins (16)Prot. (16) Interactants (458)Interact. (458) Wiki
XB-GENEPAGE-6492273
???displayGene.symbol???:
 cdkn1b

???displayGene.name???: 
cyclin-dependent kinase inhibitor 1B (p27, Kip1)

???displayGene.synonyms???
cdkn4 , kip1 , LOC108710741 , LOC492306 , men1b , men4 [+] ( Nomenclature history )

AI Protein Function :
cdkn1b encodes a nuclear cyclin‑dependent kinase inhibitor that binds and blocks CDK2‑cyclin E/A complexes, thereby enforcing G1 arrest and regulating cell proliferation; it is required for proper neur...[+]


InterPro :
CDI dom, CDI dom sf

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
multiple endocrine neoplasia type 4

MIM:
MULTIPLE ENDOCRINE NEOPLASIA, TYPE IV; MEN4

External Links:
1/2
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info