Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (62)Lit. (62) GO Terms (9)GO (9) Nucleotides (33)Nucl. (33) Proteins (17)Prot. (17) Interactants (662)Interact. (662) Wiki
XB-GENEPAGE-6054494
???displayGene.symbol???:
 ptpn11

???displayGene.name???: 
protein tyrosine phosphatase, non-receptor type 11

???displayGene.synonyms???
bptp3 , cfc , corkscrew , csw , LOC108716965 , ns1 [+] ( Nomenclature history )

???displayGene.geneFunction???
codes for a signaling molecule that is predicted to regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation

AI Protein Function :
ptpn11 encodes a cytoplasmic protein tyrosine phosphatase that acts as a signaling molecule, positively regulating fibroblast growth factor and epidermal growth factor pathways and the MAPK/ERK cascade...[+]


InterPro :
Prot-tyrosine phosphatase-like, PTP cat, SH2, SH2 dom sf, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia [+]

MIM:
JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info