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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (11)GO (11) Nucleotides (46)Nucl. (46) Proteins (27)Prot. (27) Interactants (157)Interact. (157) Wiki
XB-GENEPAGE-5721344
???displayGene.symbol???:
 wwox

???displayGene.name???: 
WW domain containing oxidoreductase

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( Nomenclature history )

???displayGene.geneFunction???
ubiquitin protein ligase

AI Protein Function :
wwox encodes a WW domain‑containing oxidoreductase that acts as a tumor suppressor, modulates apoptosis, DNA damage response and transcription through interaction with p53 and other transcription regul...[+]


InterPro :
NAD(P)-bd dom sf, SDR fam, WW dom, WW dom sf

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Diseases: 


Disease Ontology:
autosomal recessive spinocerebellar ataxia 12 [+]

MIM:
ESOPHAGEAL CANCER [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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