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Summary Expression Expr. PhenotypesPheno. Gene Literature (52)Lit. (52) GO Terms (80)GO (80) Nucleotides (122)Nucl. (122) Proteins (58)Prot. (58) Interactants (501)Interact. (501) Wiki
XB-GENEPAGE-485116
???displayGene.symbol???:
 lrp5

???displayGene.name???: 
LDL receptor related protein 5

???displayGene.synonyms???
bmnd1 , evr1 , evr4 , hbm , lr3 , lrp7 [+] ( Nomenclature history )

???displayGene.geneFunction???
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

AI Protein Function :
lrp5 encodes a single‑pass type I membrane receptor that acts as a co‑receptor for canonical Wnt ligands, mediating β‑catenin signaling. The protein localizes to the plasma membrane. Expression is obse...[+]


InterPro :
LDLR classB rpt, LDL receptor-like sf, LDLR class-A CS, LDrepeatLR classA rpt, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

MIM:
OSTEOPOROSIS [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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