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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (16)Lit. (16) GO Terms (78)GO (78) Nucleotides (162)Nucl. (162) Proteins (71)Prot. (71) Interactants (279)Interact. (279) Wiki
XB-GENEPAGE-955451
???displayGene.symbol???:
 tbk1

???displayGene.name???: 
TANK binding kinase 1

???displayGene.synonyms???
nak , t2k ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
tbk1 encodes a serine/threonine protein kinase that functions in innate immune signaling by phosphorylating irf3 and activating nf‑kb pathways, thereby promoting type i interferon production and antivi...[+]


InterPro :
Kinase-like dom sf, Ubiquitin-like domsf, TBK1 ULD, Protein kinase ATP BS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
frontotemporal dementia and/or amyotrophic lateral sclerosis 4

MIM:
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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