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Summary Expression Expr. PhenotypesPheno. Gene Literature (13)Lit. (13) GO Terms (42)GO (42) Nucleotides (228)Nucl. (228) Proteins (43)Prot. (43) Interactants (263)Interact. (263) Wiki
XB-GENEPAGE-954260
???displayGene.symbol???:
 ldlrap1

???displayGene.name???: 
low density lipoprotein receptor adaptor protein 1

???displayGene.synonyms???
arh , arh1 , fhcb1 , fhcb2 , ldlrap1-a , ldlrap1-b [+] ( Nomenclature history )

???displayGene.geneFunction???
Adaptor protein CED-6, contains PTB domain

AI Protein Function :
ldlrap1 encodes an adaptor protein that mediates clathrin‑dependent endocytosis of low‑density lipoprotein receptors, facilitating LDL uptake and cholesterol regulation; the protein contains a phosphot...[+]


InterPro :
PH-like dom sf, PTB/PI dom, Adapter Engulfment-Domain

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autosomal recessive hypercholesterolemia

MIM:
HYPERCHOLESTEROLEMIA, FAMILIAL, 4; FHCL4

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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