Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (4)Lit. (4) GO Terms (30)GO (30) Nucleotides (134)Nucl. (134) Proteins (40)Prot. (40) Interactants (571)Interact. (571) Wiki
XB-GENEPAGE-482850
???displayGene.symbol???:
 spred1

???displayGene.name???: 
sprouty related, EVH1 domain containing 1

???displayGene.synonyms???
Xspred1 , Xtspred1 ( Nomenclature history )

???displayGene.geneFunction???
regulation of signal transduction

AI Protein Function :
spred1 encodes a Sprouty‑related EVH1 domain‑containing signaling adaptor that functions as a negative regulator of the Ras/MAPK pathway, modulating FGF‑induced MAPK activation during early development...[+]


InterPro :
KBD, Sprouty, PH-like dom sf, SPRE EVH1, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Legius syndrome

MIM:
LEGIUS SYNDROME; LGSS

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info