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Summary Expression Expr. PhenotypesPheno. Gene Literature (15)Lit. (15) GO Terms (23)GO (23) Nucleotides (61)Nucl. (61) Proteins (32)Prot. (32) Interactants (188)Interact. (188) Wiki
XB-GENEPAGE-5961054
???displayGene.symbol???:
 rspo1

???displayGene.name???: 
R-spondin 1

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Subtilisin-like proprotein convertase

AI Protein Function :
rspo1 encodes a secreted Wnt signaling agonist that enhances canonical Wnt/β‑catenin activity, promotes limb bud outgrowth, drives pronephric tubule morphogenesis and supports genital ridge development...[+]


InterPro :
TSP1 rpt, TSP1 rpt sf, Furin repeat, Growth fac rcpt cys sf, [+]

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Diseases: 


MIM:
PALMOPLANTAR HYPERKERATOSIS WITH SQUAMOUS CELL CARCINOMA OF SKIN AND 46,XX SEX R

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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