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Summary Expression Expr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (15)GO (15) Nucleotides (271)Nucl. (271) Proteins (86)Prot. (86) Interactants (297)Interact. (297) Wiki
XB-GENEPAGE-485386
???displayGene.symbol???:
 arhgef12

???displayGene.name???: 
Rho guanine nucleotide exchange factor 12

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Larg ( Nomenclature history )

???displayGene.geneFunction???
PDZ-domain containing guanine exchange factor

AI Protein Function :
arhgef12 is a Rho guanine nucleotide exchange factor that activates RhoA and downstream actin cytoskeleton remodeling. It functions as a signaling molecule in pathways controlling cell shape, migration...[+]


InterPro :
RGS-like dom, RGS sf, ARHGEF12 PH, PDZ, [+]

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Diseases: 


Disease Ontology:
acute myeloid leukemia

MIM:
LEUKEMIA, ACUTE MYELOID; AML

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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