Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (31)Lit. (31) GO Terms (140)GO (140) Nucleotides (124)Nucl. (124) Proteins (52)Prot. (52) Interactants (353)Interact. (353) Wiki
XB-GENEPAGE-494739
???displayGene.symbol???:
 mecp2

???displayGene.name???: 
methyl-CpG binding protein 2

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
methyl-CpG binding transcription factor

AI Protein Function :
mecp2 encodes a methyl‑CpG‑binding transcriptional repressor that localizes to the nucleus and associates with chromatin. It binds methylated DNA and recruits corepressor complexes to modulate transcri...[+]


InterPro :
Methyl CpG DNA-bd, Me CpG-bd MeCP2, DNA-bd dom sf, MeCP2/MBD4

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
non-syndromic X-linked intellectual disability [+]

MIM:
ANGELMAN SYNDROME; AS [+]

External Links:
1/5
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info