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Summary Expression Expr. PhenotypesPheno. Gene Literature (34)Lit. (34) GO Terms (49)GO (49) Nucleotides (195)Nucl. (195) Proteins (52)Prot. (52) Interactants (552)Interact. (552) Wiki
XB-GENEPAGE-978215
???displayGene.symbol???:
 dusp6

???displayGene.name???: 
dual specificity phosphatase 6

???displayGene.synonyms???
MAP kinase phosphatase , mkp3 , pyst1 , X17C ( Nomenclature history )

???displayGene.geneFunction???
MAP kinase phosphatase

AI Protein Function :
dusp6 encodes a dual‑specificity MAP kinase phosphatase that dephosphorylates activated ERK1/2, thereby attenuating FGF‑mediated MAPK signaling and regulating cell proliferation and differentiation. Th...[+]


InterPro :
TYR PHOSPHATASE DUAL dom, Rhodanese-like dom sf, MKP, Rhodanese-like dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
hypogonadotropic hypogonadism [+]

MIM:
HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA; HH7 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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