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Summary Expression Expr. PhenotypesPheno. Gene Literature (46)Lit. (46) GO Terms (167)GO (167) Nucleotides (101)Nucl. (101) Proteins (54)Prot. (54) Interactants (383)Interact. (383) Wiki
XB-GENEPAGE-920732
???displayGene.symbol???:
 insr

???displayGene.name???: 
insulin receptor

???displayGene.synonyms???
cd220 , hhf5 , insulin receptor , Xe-InsR , XTK1 , XTK1a [+] ( Nomenclature history )

???displayGene.geneFunction???
growth factor receptor, contains protein kinase domain

AI Protein Function :
insr encodes a membrane‑bound receptor tyrosine kinase that binds insulin and initiates downstream signaling cascades; the protein localizes to the plasma membrane and is internalized to endosomal comp...[+]


InterPro :
Furin repeat, Rcpt L-dom sf, Kinase-like dom sf, Tyr kinase rcpt 2 CS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Donohue syndrome [+]

MIM:
DIABETES MELLITUS, INSULIN-RESISTANT, WITH ACANTHOSIS NIGRICANS [+]

External Links:
1/2
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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