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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (26)Lit. (26) GO Terms (99)GO (99) Nucleotides (228)Nucl. (228) Proteins (71)Prot. (71) Interactants (277)Interact. (277) Wiki
XB-GENEPAGE-481529
???displayGene.symbol???:
 map3k7

???displayGene.name???: 
mitogen-activated protein kinase kinase kinase 7

???displayGene.synonyms???
MAPKKK , tak1 , xTAK1 ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
map3k7 is a serine/threonine protein kinase that functions as a signaling molecule activating MAPK and NF‑κB cascades, phosphorylating downstream MAP2K and IKK complexes to regulate cytokine‑mediated t...[+]


InterPro :
Protein kinase ATP BS, Ser-Thr/Tyr kinase cat dom, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
frontometaphyseal dysplasia 2

MIM:
CARDIOSPONDYLOCARPOFACIAL SYNDROME; CSCF [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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