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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (32)GO (32) Nucleotides (160)Nucl. (160) Proteins (50)Prot. (50) Interactants (46)Interact. (46) Wiki
XB-GENEPAGE-967012
???displayGene.symbol???:
 tdp2

???displayGene.name???: 
tyrosyl-DNA phosphodiesterase 2

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ad022 , eap2 , ttrap ( Nomenclature history )

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Predicted Mg2+-dependent phosphodiesterase TTRAP

AI Protein Function :
tdp2 is a DNA repair enzyme that hydrolyzes 5′‑phosphotyrosyl bonds and removes covalent topoisomerase‑II–DNA adducts, thereby contributing to genome stability. It functions as a tyrosyl‑DNA phosphodie...[+]


InterPro :
Endo/exonuclease/phosphatase, Endo/exonu/phosph ase sf, TDP2-like

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Diseases: 


Disease Ontology:
autosomal recessive spinocerebellar ataxia 23

MIM:
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 23; SCAR23

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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