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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (11)Lit. (11) GO Terms (49)GO (49) Nucleotides (185)Nucl. (185) Proteins (54)Prot. (54) Interactants (302)Interact. (302) Wiki
XB-GENEPAGE-1008433
???displayGene.symbol???:
 map3k1

???displayGene.name???: 
mitogen-activated protein kinase kinase kinase 1

???displayGene.synonyms???
mapkkk1 , mekk , mekk1 ( Nomenclature history )

???displayGene.geneFunction???
MEKK and related serine/threonine protein kinases

AI Protein Function :
map3k1 is a serine/threonine protein kinase that acts as a signaling molecule in the MAPK cascade, phosphorylating downstream MAP2Ks to activate JNK and p38 pathways and thereby influencing cell migrat...[+]


InterPro :
ARM-like, Kinase-like dom sf, MAP kinase kinase kinase, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
46,XY complete gonadal dysgenesis [+]

MIM:
46,XY SEX REVERSAL 6; SRXY6

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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