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Summary Expression Expr. PhenotypesPheno. Gene Literature (19)Lit. (19) GO Terms (146)GO (146) Nucleotides (141)Nucl. (141) Proteins (68)Prot. (68) Interactants (197)Interact. (197) Wiki
XB-GENEPAGE-488023
???displayGene.symbol???:
 nf1

???displayGene.name???: 
neurofibromin 1

???displayGene.synonyms???
neurofibromin ( Nomenclature history )

???displayGene.geneFunction???
GAP, GTPase activating protein

AI Protein Function :
nf1 encodes a Ras GTPase‑activating protein that acts as a negative regulator of Ras‑MAPK signaling, thereby modulating cell proliferation, differentiation and neuronal development; the protein is loca...[+]


InterPro :
RasGAP dom, Rho GTPase activation prot, CRAL-TRIO dom, PH-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia [+]

MIM:
NEUROFIBROMATOSIS, TYPE I; NF1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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