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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (163)Lit. (163) GO Terms (72)GO (72) Nucleotides (102)Nucl. (102) Proteins (50)Prot. (50) Interactants (523)Interact. (523) Wiki
XB-GENEPAGE-1012721
???displayGene.symbol???:
 atr

???displayGene.name???: 
ATR serine/threonine kinase

???displayGene.synonyms???
frp1 , mec1 , sckl , sckl1 , xatr [-] ( Nomenclature history )

???displayGene.geneFunction???
Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination

AI Protein Function :
atr encodes a PI3/PI4‑related serine/threonine protein kinase that functions in the DNA‑damage checkpoint pathway, phosphorylates downstream effectors such as chk1 and h2ax, and regulates cell‑cycle pr...[+]


InterPro :
Kinase-like dom sf, PI3/4 kinase cat dom, PI3/4 kinase cat sf, PI3/4 kinase CS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Seckel syndrome [+]

MIM:
SECKEL SYNDROME 1; SCKL1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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