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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (22)GO (22) Nucleotides (125)Nucl. (125) Proteins (50)Prot. (50) Interactants (21)Interact. (21) Wiki
XB-GENEPAGE-995375
???displayGene.symbol???:
 c1r

???displayGene.name???: 
complement C1r

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( Nomenclature history )

???displayGene.geneFunction???
Trypsin

AI Protein Function :
c1r encodes a secreted serine protease that initiates the classical complement cascade by cleaving complement components C4 and C2, thereby generating C3 convertase and activating innate immunity. The ...[+]


InterPro :
CUB dom, EGF-like Ca-bd dom, EGF-like dom, EGF Ca-bd CS, [+]

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Diseases: 


Disease Ontology:
Ehlers-Danlos syndrome periodontal type 1

MIM:
COMPLEMENT COMPONENT C1r/C1s DEFICIENCY [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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