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Summary Expression Expr. PhenotypesPheno. Gene Literature (16)Lit. (16) GO Terms (23)GO (23) Nucleotides (109)Nucl. (109) Proteins (44)Prot. (44) Interactants (347)Interact. (347) Wiki
XB-GENEPAGE-5937935
???displayGene.symbol???:
 znrf3

???displayGene.name???: 
zinc and ring finger 3

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( Nomenclature history )

???displayGene.geneFunction???
Predicted E3 ubiquitin ligase

AI Protein Function :
znrf3 encodes a transmembrane E3 ubiquitin ligase that negatively regulates Wnt/β‑catenin signaling by promoting degradation of Frizzled receptors. The protein localizes to the plasma membrane and endo...[+]


InterPro :
Znf RING, Znf RING/FYVE/PHD, ZNRF-3 ecto, ZNRF3 Arkadia E3 ligases

???displayGene.geneInteractants???
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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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