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Summary Expression Expr. PhenotypesPheno. Gene Literature (7)Lit. (7) GO Terms (22)GO (22) Nucleotides (95)Nucl. (95) Proteins (61)Prot. (61) Interactants (219)Interact. (219) Wiki
XB-GENEPAGE-6039486
???displayGene.symbol???:
 plekhg5

???displayGene.name???: 
pleckstrin homology and RhoGEF domain containing G5

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( Nomenclature history )

???displayGene.geneFunction???
Predicted guanine nucleotide exchange factor

AI Protein Function :
plekhg5 is a Rho guanine nucleotide exchange factor signaling molecule that activates RhoA and modulates actin cytoskeleton dynamics; it localizes to the cytoplasm and plasma membrane; expression is de...[+]


InterPro :
DH-domain, PH domain, DBL dom sf, Ubiquitin-like domsf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Charcot-Marie-Tooth disease recessive intermediate C [+]

MIM:
NEURONOPATHY, DISTAL HEREDITARY MOTOR, AUTOSOMAL RECESSIVE 4; HMNR4 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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