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Summary Expression Expr. PhenotypesPheno. Gene Literature (28)Lit. (28) GO Terms (102)GO (102) Nucleotides (292)Nucl. (292) Proteins (200)Prot. (200) Interactants (667)Interact. (667) Wiki
XB-GENEPAGE-485974
???displayGene.symbol???:
 tcf7l2

???displayGene.name???: 
transcription factor 7 like 2

???displayGene.synonyms???
LOC108697306 , tcf4 , tcf4e , XTCF-4 ( Nomenclature history )

???displayGene.geneFunction???
high mobility group transcription factor

AI Protein Function :
tcf7l2 is a nuclear HMG‑box transcription factor that functions as a downstream effector of canonical Wnt/β‑catenin signaling; it activates target gene expression during early dorsal mesoderm specifica...[+]


InterPro :
Catenin binding dom sf, TCF/LEF, CTNNB1-bd N, HMG box dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
type 2 diabetes mellitus

MIM:
TYPE 2 DIABETES MELLITUS; T2D

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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