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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (7)Lit. (7) GO Terms (117)GO (117) Nucleotides (96)Nucl. (96) Proteins (47)Prot. (47) Interactants (261)Interact. (261) Wiki
XB-GENEPAGE-494613
???displayGene.symbol???:
 prkdc

???displayGene.name???: 
protein kinase, DNA-activated, catalytic subunit

???displayGene.synonyms???
dnapk , dna-pkcs , dnpk1 , hyrc , hyrc1 , p350 [+] ( Nomenclature history )

???displayGene.geneFunction???
DNA-dependent protein kinase

AI Protein Function :
prkdc encodes the catalytic subunit of DNA‑dependent protein kinase, a serine/threonine protein kinase. It mediates non‑homologous end joining of DNA double‑strand breaks and is required for V(D)J reco...[+]


InterPro :
Kinase-like dom sf, PIK FAT, DNA-PK dom, PI3/4 kinase cat dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
immunodeficiency 26

MIM:
IMMUNODEFICIENCY 26 WITH OR WITHOUT NEUROLOGIC ABNORMALITIES; IMD26

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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